Cargando…

How to create state-of-the-art genetic model systems: strategies for optimal CRISPR-mediated genome editing

Model systems with defined genetic modifications are powerful tools for basic research and translational disease modelling. Fortunately, generating state-of-the-art genetic model systems is becoming more accessible to non-geneticists due to advances in genome editing technologies. As a consequence,...

Descripción completa

Detalles Bibliográficos
Autores principales: Bollen, Yannik, Post, Jasmin, Koo, Bon-Kyoung, Snippert, Hugo J G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061873/
https://www.ncbi.nlm.nih.gov/pubmed/29955892
http://dx.doi.org/10.1093/nar/gky571