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How to create state-of-the-art genetic model systems: strategies for optimal CRISPR-mediated genome editing
Model systems with defined genetic modifications are powerful tools for basic research and translational disease modelling. Fortunately, generating state-of-the-art genetic model systems is becoming more accessible to non-geneticists due to advances in genome editing technologies. As a consequence,...
Autores principales: | Bollen, Yannik, Post, Jasmin, Koo, Bon-Kyoung, Snippert, Hugo J G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061873/ https://www.ncbi.nlm.nih.gov/pubmed/29955892 http://dx.doi.org/10.1093/nar/gky571 |
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