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Total Synthesis of Salimabromide: A Tetracyclic Polyketide from a Marine Myxobacterium

[Image: see text] Salimabromide is an antibiotic polyketide that was previously isolated from the obligate marine myxobacterium Enhygromyxa salina, and its densely functionalized and conformationally rigid tetracyclic framework is unprecedented in nature. Herein we report the first chemical synthesi...

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Detalles Bibliográficos
Autores principales: Schmid, Matthias, Grossmann, Adriana S., Wurst, Klaus, Magauer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061937/
https://www.ncbi.nlm.nih.gov/pubmed/29953216
http://dx.doi.org/10.1021/jacs.8b06228