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Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward
The gut-to-brain axis exhibits significant control over motivated behavior. However, mechanisms supporting this communication are poorly understood. We reveal that a gut-based bariatric surgery chronically elevates systemic bile acids and attenuates cocaine-induced elevations in accumbal dopamine. N...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061973/ https://www.ncbi.nlm.nih.gov/pubmed/30048457 http://dx.doi.org/10.1371/journal.pbio.2006682 |