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Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward
The gut-to-brain axis exhibits significant control over motivated behavior. However, mechanisms supporting this communication are poorly understood. We reveal that a gut-based bariatric surgery chronically elevates systemic bile acids and attenuates cocaine-induced elevations in accumbal dopamine. N...
Autores principales: | Reddy, India A., Smith, Nicholas K., Erreger, Kevin, Ghose, Dipanwita, Saunders, Christine, Foster, Daniel J., Turner, Brandon, Poe, Amanda, Albaugh, Vance L., McGuinness, Owen, Hackett, Troy A., Grueter, Brad A., Abumrad, Naji N., Flynn, Charles Robb, Galli, Aurelio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061973/ https://www.ncbi.nlm.nih.gov/pubmed/30048457 http://dx.doi.org/10.1371/journal.pbio.2006682 |
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