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Distribution of KRAS, DDR2, and TP53 gene mutations in lung cancer: An analysis of Iranian patients

PURPOSE: Lung cancer is the deadliest known cancer in the world, with the highest number of mutations in proto-oncogenes and tumor suppressor genes. Therefore, this study was conducted to determine the status of hotspot regions in DDR2 and KRAS genes for the first time, as well as in TP53 gene, in l...

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Detalles Bibliográficos
Autores principales: Fathi, Zahra, Mousavi, Seyed Ali Javad, Roudi, Raheleh, Ghazi, Farideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061986/
https://www.ncbi.nlm.nih.gov/pubmed/30048458
http://dx.doi.org/10.1371/journal.pone.0200633