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Testing an optimally weighted combination of common and/or rare variants with multiple traits
Recently, joint analysis of multiple traits has become popular because it can increase statistical power to identify genetic variants associated with complex diseases. In addition, there is increasing evidence indicating that pleiotropy is a widespread phenomenon in complex diseases. Currently, most...
Autores principales: | Wang, Zhenchuan, Sha, Qiuying, Fang, Shurong, Zhang, Kui, Zhang, Shuanglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062080/ https://www.ncbi.nlm.nih.gov/pubmed/30048520 http://dx.doi.org/10.1371/journal.pone.0201186 |
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