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A 3D diffusional-compartmental model of the calcium dynamics in cytosol, sarcoplasmic reticulum and mitochondria of murine skeletal muscle fibers

Variations of free calcium concentration ([Ca(2+)]) are powerful intracellular signals, controlling contraction as well as metabolism in muscle cells. To fully understand the role of calcium redistribution upon excitation and contraction in skeletal muscle cells, the local [Ca(2+)] in different comp...

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Detalles Bibliográficos
Autores principales: Marcucci, Lorenzo, Canato, Marta, Protasi, Feliciano, Stienen, Ger J. M., Reggiani, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062086/
https://www.ncbi.nlm.nih.gov/pubmed/30048500
http://dx.doi.org/10.1371/journal.pone.0201050