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A 3D diffusional-compartmental model of the calcium dynamics in cytosol, sarcoplasmic reticulum and mitochondria of murine skeletal muscle fibers
Variations of free calcium concentration ([Ca(2+)]) are powerful intracellular signals, controlling contraction as well as metabolism in muscle cells. To fully understand the role of calcium redistribution upon excitation and contraction in skeletal muscle cells, the local [Ca(2+)] in different comp...
Autores principales: | Marcucci, Lorenzo, Canato, Marta, Protasi, Feliciano, Stienen, Ger J. M., Reggiani, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062086/ https://www.ncbi.nlm.nih.gov/pubmed/30048500 http://dx.doi.org/10.1371/journal.pone.0201050 |
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