Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data

Chemogenomic approaches involving highly annotated compound sets and cell based high throughput screening are emerging as a means to identify novel drug targets. We have previously screened a collection of highly characterized kinase inhibitors (Khan et al., Journal of General Virology, 2016) to ide...

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Detalles Bibliográficos
Autores principales: Strang, Blair L., Asquith, Christopher R. M., Moshrif, Hanan F., Ho, Catherine M-K, Zuercher, William J., Al-Ali, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062112/
https://www.ncbi.nlm.nih.gov/pubmed/30048526
http://dx.doi.org/10.1371/journal.pone.0201321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062112/
https://www.ncbi.nlm.nih.gov/pubmed/30048526
http://dx.doi.org/10.1371/journal.pone.0201321

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