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Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons

Oxygenated polycyclic aromatic hydrocarbons (oxy-PAHs) are found in the environment together with PAHs. However, less is known concerning their biological activity including their impact on aryl hydrocarbon receptor (AHR) signalling and the subsequent modulation of the cytochrome P450 monooxygenases...

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Detalles Bibliográficos
Autores principales: Wincent, Emma, Le Bihanic, Florane, Dreij, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062249/
https://www.ncbi.nlm.nih.gov/pubmed/30090389
http://dx.doi.org/10.1039/c6tx00004e