NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene

Fused in sarcoma (FUS) was identified as a component of typical inclusions in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). In FTLD, both nuclear and cytoplasmic inclusions with wild-type FUS exist, while cytoplasmic inclusions with a mutant-form of FUS occur in m...

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Detalles Bibliográficos
Autores principales: Yamamoto, Itaru, Azuma, Yumiko, Kushimura, Yukie, Yoshida, Hideki, Mizuta, Ikuko, Mizuno, Toshiki, Ueyama, Morio, Nagai, Yoshitaka, Tokuda, Takahiko, Yamaguchi, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062494/
https://www.ncbi.nlm.nih.gov/pubmed/30050143
http://dx.doi.org/10.1038/s41598-018-29716-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062494/
https://www.ncbi.nlm.nih.gov/pubmed/30050143
http://dx.doi.org/10.1038/s41598-018-29716-9

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