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Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7–CYFIP1-mediated signaling pathway

The early onset breast cancer patients (age ≤ 40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the late-onset patients. To identify the genes and molecules associated with poor prognosis of early onset breast cancer, we examined gene expression...

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Detalles Bibliográficos
Autores principales: Chang, Jer-Wei, Kuo, Wen-Hung, Lin, Chiao-Mei, Chen, Wen-Ling, Chan, Shih-Hsuan, Chiu, Meng-Fan, Chang, I-Shou, Jiang, Shih-Sheng, Tsai, Fang-Yu, Chen, Chung-Hsing, Huang, Pei-Hsin, Chang, King-Jen, Lin, Kai-Ti, Lin, Sheng-Chieh, Wang, Ming-Yang, Uen, Yih-Huei, Tu, Chi-Wen, Hou, Ming-Feng, Tsai, Shih-Feng, Shen, Chen-Yang, Tung, Shiao-Lin, Wang, Lu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062498/
https://www.ncbi.nlm.nih.gov/pubmed/29706651
http://dx.doi.org/10.1038/s41388-018-0253-9