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AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy

The synapse between inner hair cells (IHCs) and type I spiral ganglion neurons (SGNs) has been identified as a sensitive structure to noise-induced damage in the mammalian cochlea. Since this synapse provides the major information pathway from the cochlea to the auditory brain, it is important to ma...

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Detalles Bibliográficos
Autores principales: Chen, Hengchao, Xing, Yazhi, Xia, Li, Chen, Zhengnong, Yin, Shankai, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062503/
https://www.ncbi.nlm.nih.gov/pubmed/29535374
http://dx.doi.org/10.1038/s41434-018-0012-0