Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity

Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure and remains a critical problem in medicine. PARP1-dependent poly(ADPribosyl)ation is a key mediator of cellular stress responses and functions in multiple physiological and pathological processes. However, whether it is...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Xu, Wenjing, Zhang, Yanqing, Huang, Dan, Huang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062506/
https://www.ncbi.nlm.nih.gov/pubmed/30050067
http://dx.doi.org/10.1038/s41419-018-0875-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062506/
https://www.ncbi.nlm.nih.gov/pubmed/30050067
http://dx.doi.org/10.1038/s41419-018-0875-4

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