Computational Design of Epitope-Enriched HIV-1 Gag Antigens with Preserved Structure and Function for Induction of Broad CD8(+) T Cell Responses

The partially protective phenotype observed in HIV-infected long-term-non-progressors is often associated with certain HLA alleles, thus indicating that cytotoxic T lymphocyte (CTL) responses play a crucial role in combating virus replication. However, both the vast variability of HIV and the HLA di...

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Detalles Bibliográficos
Autores principales: Asbach, Benedikt, Meier, Johannes P., Pfeifer, Matthias, Köstler, Josef, Wagner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062507/
https://www.ncbi.nlm.nih.gov/pubmed/30050069
http://dx.doi.org/10.1038/s41598-018-29435-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062507/
https://www.ncbi.nlm.nih.gov/pubmed/30050069
http://dx.doi.org/10.1038/s41598-018-29435-1

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