Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1

Necroptosis complements apoptosis as a host defense pathway to stop virus infection. Herpes simplex virus shows a propensity to trigger necroptosis of mouse cells and mice even though cell death is blocked in human cells through UL39-encoded ICP6. This ribonucleotide reductase large subunit (R1) nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Hongyan, Gilley, Ryan P., Fisher, Amanda, Lane, Rebecca, Landsteiner, Vanessa J., Ragan, Katherine B., Dovey, Cole M., Carette, Jan E., Upton, Jason W., Mocarski, Edward S., Kaiser, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062522/
https://www.ncbi.nlm.nih.gov/pubmed/30050136
http://dx.doi.org/10.1038/s41419-018-0868-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062522/
https://www.ncbi.nlm.nih.gov/pubmed/30050136
http://dx.doi.org/10.1038/s41419-018-0868-3

Ejemplares similares