Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates

Transcription by RNA polymerase (RNAP) is interspersed with sequence-dependent pausing. The processes through which paused states are accessed and stabilized occur at spatiotemporal scales beyond the resolution of previous methods, and are poorly understood. Here, we combine high-resolution optical...

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Detalles Bibliográficos
Autores principales: Gabizon, Ronen, Lee, Antony, Vahedian-Movahed, Hanif, Ebright, Richard H., Bustamante, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062546/
https://www.ncbi.nlm.nih.gov/pubmed/30050038
http://dx.doi.org/10.1038/s41467-018-05344-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062546/
https://www.ncbi.nlm.nih.gov/pubmed/30050038
http://dx.doi.org/10.1038/s41467-018-05344-9

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