Cargando…
Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates
Transcription by RNA polymerase (RNAP) is interspersed with sequence-dependent pausing. The processes through which paused states are accessed and stabilized occur at spatiotemporal scales beyond the resolution of previous methods, and are poorly understood. Here, we combine high-resolution optical...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062546/ https://www.ncbi.nlm.nih.gov/pubmed/30050038 http://dx.doi.org/10.1038/s41467-018-05344-9 |