Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a glycans

We have previously reported clinical data to suggest that colonization factor I (CFA/I) fimbriae of enterotoxigenic Escherichia coli (ETEC) can bind to Lewis a (Le(a)), a glycan epitope ubiquitous in the small intestinal mucosa of young children (<2 years of age), and individuals with a genetic m...

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Detalles Bibliográficos
Autores principales: Mottram, Lynda, Liu, Jining, Chavan, Sonali, Tobias, Joshua, Svennerholm, Ann-Mari, Holgersson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062558/
https://www.ncbi.nlm.nih.gov/pubmed/30050155
http://dx.doi.org/10.1038/s41598-018-29258-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062558/
https://www.ncbi.nlm.nih.gov/pubmed/30050155
http://dx.doi.org/10.1038/s41598-018-29258-0

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