PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart

Cardiac hypertrophy occurs in response to increased hemodynamic demand and can progress to heart failure. Identifying the key regulators of this process is clinically important. Though it is thought that the phosphorylation of histone deacetylase (HDAC) 2 plays a crucial role in the development of p...

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Detalles Bibliográficos
Autores principales: Yoon, Somy, Kook, Taewon, Min, Hyun-Ki, Kwon, Duk-Hwa, Cho, Young Kuk, Kim, Mira, Shin, Sera, Joung, Hosouk, Jeong, Seung Hoon, Lee, Sumin, Kang, Gaeun, Park, Yunchul, Kim, Yong Sook, Ahn, Youngkeun, McMullen, Julie R., Gergs, Ulrich, Neumann, Joachim, Kim, Kyung Keun, Kim, Jungchul, Nam, Kwang-Il, Kim, Young-Kook, Kook, Hyun, Eom, Gwang Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062565/
https://www.ncbi.nlm.nih.gov/pubmed/30050113
http://dx.doi.org/10.1038/s12276-018-0121-2

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