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Intrathecal B Cells in MS Have Significantly Greater Lymphangiogenic Potential Compared to B Cells Derived From Non-MS Subjects

Although B cell depletion is an effective therapy of multiple sclerosis (MS), the pathogenic functions of B cells in MS remain incompletely understood. We asked whether cerebrospinal fluid (CSF) B cells in MS secrete different cytokines than control-subject B cells and whether cytokine secretion aff...

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Detalles Bibliográficos
Autores principales: Stein, Jason, Xu, Quangang, Jackson, Kayla C., Romm, Elena, Wuest, Simone C., Kosa, Peter, Wu, Tianxia, Bielekova, Bibiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062589/
https://www.ncbi.nlm.nih.gov/pubmed/30079049
http://dx.doi.org/10.3389/fneur.2018.00554