Cargando…
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
The endosomal sorting complex required for transport (ESCRT) machinery mediates cargo sorting, membrane deformation and membrane scission on the surface of endosomes, generating intraluminal vesicles (ILVs) to degrade signaling receptors. By live-cell imaging of individual endosomes in human cells,...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062606/ https://www.ncbi.nlm.nih.gov/pubmed/30050131 http://dx.doi.org/10.1038/s41467-018-05345-8 |