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Functional expression of TLR5 of different vertebrate species and diversification in intestinal pathogen recognition

Toll-like receptor 5 (TLR5) is activated by bacterial flagellins and plays a crucial role in the first-line defence against pathogenic bacteria and in immune homeostasis, and is highly conserved in vertebrate species. However, little comparative information is available on TLR5 functionality. In thi...

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Detalles Bibliográficos
Autores principales: Faber, Eugenia, Tedin, Karsten, Speidel, Yvonne, Brinkmann, Melanie M., Josenhans, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062626/
https://www.ncbi.nlm.nih.gov/pubmed/30050158
http://dx.doi.org/10.1038/s41598-018-29371-0