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Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer’s disease

Oxidative modification of the voltage-gated K(+) channel subfamily B member 1 (KCNB1, Kv2.1) is emerging as a mechanism of neuronal vulnerability potentially capable of affecting multiple conditions associated with oxidative stress, from normal aging to neurodegenerative disease. In this study we re...

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Detalles Bibliográficos
Autores principales: Wei, Yu, Shin, Mi Ryung, Sesti, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062629/
https://www.ncbi.nlm.nih.gov/pubmed/30050035
http://dx.doi.org/10.1038/s41419-018-0886-1

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