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Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells

BACKGROUND: Hematopoietic lineage cells derived from human pluripotent stem cells (hPSCs) hold great promise for the treatment of hematological diseases and providing sufficient cells for immune therapy. However, a simple, cost-effective method to generate large quantities of hematopoietic stem/prog...

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Detalles Bibliográficos
Autores principales: Duan, Fuyu, Huang, Rujin, Zhang, Fengzhi, Zhu, Yonglin, Wang, Lin, Chen, Xia, Bai, Lufeng, Guo, Wei, Chang, Sophia Chia-Ning, Hu, Xiaoyu, Na, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062919/
https://www.ncbi.nlm.nih.gov/pubmed/30053898
http://dx.doi.org/10.1186/s13287-018-0934-x