Trans-heterozygosity for mutations enhances the risk of recurrent/chronic pancreatitis in patients with Cystic Fibrosis

BACKGROUND: Recurrent (RP) and chronic pancreatitis (CP) may complicate Cystic Fibrosis (CF). It is still unknown if mutations in genes involved in the intrapancreatic activation of trypsin (IPAT) or in the pancreatic secretion pathway (PSP) may enhance the risk for RP/CP in patients with CF. METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales: Sofia, Valentina Maria, Surace, Cecilia, Terlizzi, Vito, Da Sacco, Letizia, Alghisi, Federico, Angiolillo, Antonella, Braggion, Cesare, Cirilli, Natalia, Colombo, Carla, Di Lullo, Antonella, Padoan, Rita, Quattrucci, Serena, Raia, Valeria, Tuccio, Giuseppe, Zarrilli, Federica, Tomaiuolo, Anna Cristina, Novelli, Antonio, Lucidi, Vincenzina, Lucarelli, Marco, Castaldo, Giuseppe, Angioni, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062922/
https://www.ncbi.nlm.nih.gov/pubmed/30134826
http://dx.doi.org/10.1186/s10020-018-0041-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062922/
https://www.ncbi.nlm.nih.gov/pubmed/30134826
http://dx.doi.org/10.1186/s10020-018-0041-6

Ejemplares similares