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Positive cofactor 4 (PC4) contributes to the regulation of replication-dependent canonical histone gene expression

BACKGROUND: Core canonical histones are required in the S phase of the cell cycle to pack newly synthetized DNA, therefore the expression of their genes is highly activated during DNA replication. In mammalian cells, this increment is achieved by both enhanced transcription and 3′ end processing. In...

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Detalles Bibliográficos
Autores principales: Brzek, Aleksandra, Cichocka, Marlena, Dolata, Jakub, Juzwa, Wojciech, Schümperli, Daniel, Raczynska, Katarzyna Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062981/
https://www.ncbi.nlm.nih.gov/pubmed/30053800
http://dx.doi.org/10.1186/s12867-018-0110-y