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Positive cofactor 4 (PC4) contributes to the regulation of replication-dependent canonical histone gene expression
BACKGROUND: Core canonical histones are required in the S phase of the cell cycle to pack newly synthetized DNA, therefore the expression of their genes is highly activated during DNA replication. In mammalian cells, this increment is achieved by both enhanced transcription and 3′ end processing. In...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062981/ https://www.ncbi.nlm.nih.gov/pubmed/30053800 http://dx.doi.org/10.1186/s12867-018-0110-y |