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Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters
BACKGROUND: Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmission of BRCA1 and MGMT promoter methylations in mother-newb...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062990/ https://www.ncbi.nlm.nih.gov/pubmed/30049288 http://dx.doi.org/10.1186/s13148-018-0529-5 |