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Methylation of BRCA1 and MGMT genes in white blood cells are transmitted from mothers to daughters

BACKGROUND: Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmission of BRCA1 and MGMT promoter methylations in mother-newb...

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Detalles Bibliográficos
Autores principales: Al-Moghrabi, Nisreen, Al-Showimi, Maram, Al-Yousef, Nujoud, Al-Shahrani, Bushra, Karakas, Bedri, Alghofaili, Lamyaa, Almubarak, Hannah, Madkhali, Safia, Al Humaidan, Hind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062990/
https://www.ncbi.nlm.nih.gov/pubmed/30049288
http://dx.doi.org/10.1186/s13148-018-0529-5