Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

BACKGROUND: Humoral immune responses to infectious agents or vaccination vary substantially among individuals, and many of the factors responsible for this variability remain to be defined. Current evidence suggests that human genetic variation influences (i) serum immunoglobulin levels, (ii) seroco...

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Detalles Bibliográficos
Autores principales: Scepanovic, Petar, Alanio, Cécile, Hammer, Christian, Hodel, Flavia, Bergstedt, Jacob, Patin, Etienne, Thorball, Christian W., Chaturvedi, Nimisha, Charbit, Bruno, Abel, Laurent, Quintana-Murci, Lluis, Duffy, Darragh, Albert, Matthew L., Fellay, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063007/
https://www.ncbi.nlm.nih.gov/pubmed/30053915
http://dx.doi.org/10.1186/s13073-018-0568-8