ProTide generated long-acting abacavir nanoformulations

Abacavir pronucleotide nanoformulations (NM3ABC) were prepared as a novel long acting slow effective release antiretroviral therapy. Single NM3ABC treatment of human monocyte-derived macrophages produced sustained intracellular carbovir-triphosphate and antiretroviral activities for up to 30 days.

Detalles Bibliográficos
Autores principales: Lin, Zhiyi, Gautam, Nagsen, Alnouti, Yazen, McMillan, JoEllyn, Bade, Aditya N., Gendelman, Howard E., Edagwa, Benson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063073/
https://www.ncbi.nlm.nih.gov/pubmed/29995046
http://dx.doi.org/10.1039/c8cc04708a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063073/
https://www.ncbi.nlm.nih.gov/pubmed/29995046
http://dx.doi.org/10.1039/c8cc04708a

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