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Analysis of Genetic Variation Indicates DNA Shape Involvement in Purifying Selection
Noncoding DNA sequences, which play various roles in gene expression and regulation, are under evolutionary pressure. Gene regulation requires specific protein–DNA binding events, and our previous studies showed that both DNA sequence and shape readout are employed by transcription factors (TFs) to...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063282/ https://www.ncbi.nlm.nih.gov/pubmed/29850830 http://dx.doi.org/10.1093/molbev/msy099 |