Adaptive Landscape of Protein Variation in Human Exomes

The human genome contains hundreds of thousands of missense mutations. However, only a handful of these variants are known to be adaptive, which implies that adaptation through protein sequence change is an extremely rare phenomenon in human evolution. Alternatively, existing methods may lack the po...

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Detalles Bibliográficos
Autores principales: Patel, Ravi, Scheinfeldt, Laura B, Sanderford, Maxwell D, Lanham, Tamera R, Tamura, Koichiro, Platt, Alexander, Glicksberg, Benjamin S, Xu, Ke, Dudley, Joel T, Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063297/
https://www.ncbi.nlm.nih.gov/pubmed/29846678
http://dx.doi.org/10.1093/molbev/msy107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063297/
https://www.ncbi.nlm.nih.gov/pubmed/29846678
http://dx.doi.org/10.1093/molbev/msy107

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