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Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex

PURPOSE: Human females have a unique duration of post-reproductive longevity, during which sex-specific mechanisms ma influence later-life mechanisms of neuronal resilience and vulnerability. The maintenance of energy metabolism, through the oxidative phosphorylation (OXPHOS) apparatus, is essential...

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Detalles Bibliográficos
Autores principales: Bove, Riley M., Patrick, Ellis, Aubin, Cristin McCabe, Srivastava, Gyan, Schneider, Julie A., Bennett, David A., De Jager, Philip L., Chibnik, Lori B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063396/
https://www.ncbi.nlm.nih.gov/pubmed/30052629
http://dx.doi.org/10.1371/journal.pone.0199073