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Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing

BACKGROUND: Hepatocellular adenomas (HCA) are benign liver tumors that may transform into hepatocellular carcinoma (HCC), but the molecular drivers of this transformation remain ill-defined. This study evaluates the molecular changes in HCA and HCC and in comparison to their adjacent non-neoplastic...

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Detalles Bibliográficos
Autores principales: Zheng, Jian, Sadot, Eran, Vigidal, Joana A., Klimstra, David S., Balachandran, Vinod P., Kingham, T. Peter, Allen, Peter J., D’Angelica, Michael I., DeMatteo, Ronald P., Jarnagin, William R., Ventura, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063411/
https://www.ncbi.nlm.nih.gov/pubmed/30052636
http://dx.doi.org/10.1371/journal.pone.0200776