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A fibrin biofilm covers blood clots and protects from microbial invasion

Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a characteristic network, interact with blood cells, and initiate tissue repair. The fibrin network is porous and highly permeable, but the spatial arrangement of the external clot face is unknown. Here we show that fibrin t...

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Detalles Bibliográficos
Autores principales: Macrae, Fraser L., Duval, Cédric, Papareddy, Praveen, Baker, Stephen R., Yuldasheva, Nadira, Kearney, Katherine J., McPherson, Helen R., Asquith, Nathan, Konings, Joke, Casini, Alessandro, Degen, Jay L., Connell, Simon D., Philippou, Helen, Wolberg, Alisa S., Herwald, Heiko, Ariëns, Robert A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063501/
https://www.ncbi.nlm.nih.gov/pubmed/29723163
http://dx.doi.org/10.1172/JCI98734