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A fibrin biofilm covers blood clots and protects from microbial invasion
Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a characteristic network, interact with blood cells, and initiate tissue repair. The fibrin network is porous and highly permeable, but the spatial arrangement of the external clot face is unknown. Here we show that fibrin t...
Autores principales: | Macrae, Fraser L., Duval, Cédric, Papareddy, Praveen, Baker, Stephen R., Yuldasheva, Nadira, Kearney, Katherine J., McPherson, Helen R., Asquith, Nathan, Konings, Joke, Casini, Alessandro, Degen, Jay L., Connell, Simon D., Philippou, Helen, Wolberg, Alisa S., Herwald, Heiko, Ariëns, Robert A.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063501/ https://www.ncbi.nlm.nih.gov/pubmed/29723163 http://dx.doi.org/10.1172/JCI98734 |
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