Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women

This tutorial presents the workflow of adapting an adult physiologically based pharmacokinetic (PBPK) model to the pregnant populations using the Open Systems Pharmacology (OSP) software suite (http://www.open-systems-pharmacology.org). This workflow is illustrated using a previously published PBPK...

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Detalles Bibliográficos
Autores principales: Dallmann, André, Solodenko, Juri, Ince, Ibrahim, Eissing, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Tutorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063743/
https://www.ncbi.nlm.nih.gov/pubmed/29569837
http://dx.doi.org/10.1002/psp4.12300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063743/
https://www.ncbi.nlm.nih.gov/pubmed/29569837
http://dx.doi.org/10.1002/psp4.12300

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