First in human evaluation of [(18)F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors

BACKGROUND: Efforts to develop suitable positron emission tomography (PET) tracers for the ion channel site of human N-methyl-d-aspartate (NMDA) receptors have had limited success. [(18)F]PK-209 is a GMOM derivative that binds to the intrachannel phencyclidine site with high affinity and selectivity...

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Detalles Bibliográficos
Autores principales: van der Aart, Jasper, Golla, Sandeep S. V., van der Pluijm, Marieke, Schwarte, Lothar A., Schuit, Robert C., Klein, Pieter J., Metaxas, Athanasios, Windhorst, Albert D., Boellaard, Ronald, Lammertsma, Adriaan A., van Berckel, Bart N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063804/
https://www.ncbi.nlm.nih.gov/pubmed/30054846
http://dx.doi.org/10.1186/s13550-018-0424-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063804/
https://www.ncbi.nlm.nih.gov/pubmed/30054846
http://dx.doi.org/10.1186/s13550-018-0424-2

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