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Control of protein degradation by N-terminal acetylation and the N-end rule pathway

Nα-terminal acetylation (Nt-acetylation) occurs very frequently and is found in most proteins in eukaryotes. Despite the pervasiveness and universality of Nt-acetylation, its general functions in terms of physiological outcomes remain largely elusive. However, several recent studies have revealed th...

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Detalles Bibliográficos
Autores principales: Nguyen, Kha The, Mun, Sang-Hyeon, Lee, Chang-Seok, Hwang, Cheol-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063864/
https://www.ncbi.nlm.nih.gov/pubmed/30054456
http://dx.doi.org/10.1038/s12276-018-0097-y