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ClpB mutants of Francisella tularensis subspecies holarctica and tularensis are defective for type VI secretion and intracellular replication

Francisella tularensis, a highly infectious, intracellular bacterium possesses an atypical type VI secretion system (T6SS), which is essential for the virulence of the bacterium. Recent data suggest that the HSP100 family member, ClpB, is involved in T6SS disassembly in the subspecies Francisella no...

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Detalles Bibliográficos
Autores principales: Alam, Athar, Golovliov, Igor, Javed, Eram, Sjöstedt, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063899/
https://www.ncbi.nlm.nih.gov/pubmed/30054549
http://dx.doi.org/10.1038/s41598-018-29745-4