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ClpB mutants of Francisella tularensis subspecies holarctica and tularensis are defective for type VI secretion and intracellular replication
Francisella tularensis, a highly infectious, intracellular bacterium possesses an atypical type VI secretion system (T6SS), which is essential for the virulence of the bacterium. Recent data suggest that the HSP100 family member, ClpB, is involved in T6SS disassembly in the subspecies Francisella no...
Autores principales: | Alam, Athar, Golovliov, Igor, Javed, Eram, Sjöstedt, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063899/ https://www.ncbi.nlm.nih.gov/pubmed/30054549 http://dx.doi.org/10.1038/s41598-018-29745-4 |
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