Metal-cation regulation of enzyme dynamics is a key factor influencing the activity of S-adenosyl-l-homocysteine hydrolase from Pseudomonas aeruginosa

S-adenosyl-l-homocysteine hydrolase from Pseudomonas aeruginosa (PaSAHase) coordinates one K(+) ion and one Zn(2+) ion in the substrate binding area. The cations affect the enzymatic activity and substrate binding but the molecular mechanisms of their action are unknown. Enzymatic and isothermal tit...

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Detalles Bibliográficos
Autores principales: Czyrko, Justyna, Sliwiak, Joanna, Imiolczyk, Barbara, Gdaniec, Zofia, Jaskolski, Mariusz, Brzezinski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063907/
https://www.ncbi.nlm.nih.gov/pubmed/30054521
http://dx.doi.org/10.1038/s41598-018-29535-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063907/
https://www.ncbi.nlm.nih.gov/pubmed/30054521
http://dx.doi.org/10.1038/s41598-018-29535-y

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