Hippo Signaling Pathway Dysregulation in Human Huntington’s Disease Brain and Neuronal Stem Cells

The Hippo signaling pathway is involved in organ size regulation and tumor suppression. Although inhibition of Hippo leads to tumorigenesis, activation of Hippo may play a role in neurodegeneration. Specifically, activation of the upstream regulator, mammalian sterile 20 (STE20)-like kinase 1 (MST1)...

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Detalles Bibliográficos
Autores principales: Mueller, Kaly A., Glajch, Kelly E., Huizenga, Megan N., Wilson, Remi A., Granucci, Eric J., Dios, Amanda M., Tousley, Adelaide R., Iuliano, Maria, Weisman, Elizabeth, LaQuaglia, Michael J., DiFiglia, Marian, Kegel-Gleason, Kimberly, Vakili, Khashayar, Sadri-Vakili, Ghazaleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063913/
https://www.ncbi.nlm.nih.gov/pubmed/30054496
http://dx.doi.org/10.1038/s41598-018-29319-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063913/
https://www.ncbi.nlm.nih.gov/pubmed/30054496
http://dx.doi.org/10.1038/s41598-018-29319-4

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