Histone deacetylase 8 protects human proximal tubular epithelial cells from hypoxia-mimetic cobalt- and hypoxia/reoxygenation-induced mitochondrial fission and cytotoxicity

Cell death by hypoxia followed by reoxygenation (H/R) is responsible for tissue injury in multiple pathological conditions. Recent studies found that epigenetic reprogramming mediated by histone deacetylases (HDACs) is implicated in H/R-induced cell death. However, among 18 different isoforms compri...

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Detalles Bibliográficos
Autores principales: Ha, Soon-Duck, Solomon, Ori, Akbari, Masoud, Sener, Alp, Kim, Sung Ouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063935/
https://www.ncbi.nlm.nih.gov/pubmed/30054507
http://dx.doi.org/10.1038/s41598-018-29463-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063935/
https://www.ncbi.nlm.nih.gov/pubmed/30054507
http://dx.doi.org/10.1038/s41598-018-29463-x

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