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Engineered Protein Model of the ATP synthase H(+)- Channel Shows No Salt Bridge at the Rotor-Stator Interface

ATP synthase is powered by the flow of protons through the molecular turbine composed of two α-helical integral membrane proteins, subunit a, which makes a stator, and a cylindrical rotor assembly made of multiple copies of subunit c. Transient protonation of a universally conserved carboxylate on s...

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Detalles Bibliográficos
Autores principales: Pierson, Hannah E., Kaler, Mandeep, O’Grady, Christopher, Uhlemann, Eva-Maria E., Dmitriev, Oleg Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063947/
https://www.ncbi.nlm.nih.gov/pubmed/30054535
http://dx.doi.org/10.1038/s41598-018-29693-z