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Spindle tubulin and MTOC asymmetries may explain meiotic drive in oocytes
In the first meiotic division (MI) of oocytes, the cortically positioned spindle causes bivalent segregation in which only the centre-facing homologue pairs are retained. ‘Selfish’ chromosomes are known to exist, which bias their spindle orientation and hence retention in the egg, a process known as...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063951/ https://www.ncbi.nlm.nih.gov/pubmed/30054463 http://dx.doi.org/10.1038/s41467-018-05338-7 |