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Absorbance measurements of oxidation of homogentisic acid accelerated by the addition of alkaline solution with sodium hypochlorite pentahydrate

The urine of patients with alkaptonuria turns dark brown due to the oxidation of homogentisic acid (HGA) to benzoquinone acetic acid (BQA), and this is accelerated by the addition of alkali. We recently reported that alkaptonuric urine and HGA after the addition of alkali showed characteristic peaks...

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Detalles Bibliográficos
Autores principales: Tokuhara, Yasunori, Shukuya, Kenichi, Tanaka, Masami, Sogabe, Keisuke, Ejima, Yasukazu, Hosokawa, Sho, Ohsaki, Hiroyuki, Morinishi, Tatsuya, Hirakawa, Eiichiro, Yatomi, Yutaka, Shimosawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063975/
https://www.ncbi.nlm.nih.gov/pubmed/30054539
http://dx.doi.org/10.1038/s41598-018-29769-w