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Soluble Expression of Humanized Anti-CD20 Single Chain Antibody in Escherichia coli by Cytoplasmic Chaperones Co-expression

BACKGROUND: CD20 is an important cell surface receptor that is used for target therapy of B cell lymphoma and some related blood diseases due to vital function of CD20. In previous studies, a Rituximab based humanized single chain variable fragment (scFv) antibody showed good reactivity against B ce...

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Detalles Bibliográficos
Autores principales: Yousefi, Mohammadreza, Farajnia, Safar, Mokhtarzadeh, Ahad, Akbari, Bahman, Ahdi Khosroshahi, Shiva, Mamipour, Mina, Dariushnejad, Hassan, Ahmadzadeh, Vahideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063999/
https://www.ncbi.nlm.nih.gov/pubmed/30090206